e-book Combinatorial Chemistry on Solid Supports

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Comb Chem High Throughput Screen. Aug;12(7) Epub Aug 1 . Combinatorial chemistry on solid support in the search for central nervous.
Table of contents

Table of Contents

A variety of compounds can be synthesized quickly upon determination of their synthetic routes. Furthermore, they have the advantage of being capable of automatic synthesis.

Currently, the reactions which can be utilized in the solid-phase syntheses are limited, however, other potentially utilizable reactions are vigorously being explored. In the other synthesis of libraries, the liquid-phase reactions are carried out utilizing conventional organic synthetic reactions.

Some developments have been reported and future developments are being anticipated.

COMBINATORIAL CHEMISTRY AND SOLID PHASE SYNTHESIS

We have put on the market various kinds of resins which have widely been utilized through the solid-phase synthetic technique and useful diphenylphosphino polystyrene resin for liquid-phase Mitsunobu reaction. Lectures, bibliographic search through serching engines, powerpoint presentations. Soluble and insoluble polymers.

Resins for solid-phase synthesis: preparation, characterization, loading, properties. Macroscopic solid supports. Solid phase synthesis: handles, linkers, loading and cleavage strategies, examples of organic reactions, analytical methods.

Combinatorial chemistry: use and applications. Deconvolutive methods and tagging. On-bead and off-bead tests. Combinatorial chemistry and material science.

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Solid-Phase Organic Synthesis: A Critical Understanding of the Resin | ACS Combinatorial Science

Literature search. Seneci; Wiley Interscience, New York.

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ISBN Atherton, R. Combinatorial chemistry and solid phase synthesis 3 ECTS.

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Composite material for biomedical applications 6 ECTS. Introduction to solid state 6 ECTS. Italian course 3 ECTS.

Content Soluble and insoluble polymers. Resins for solid-phase synthesis: preparation, characterization, loading, properties. Macroscopic solid supports.